2-Pentanone (MPK) CAS 107-87-9

Product Overview

2-Pentanone (methyl propyl ketone, MPK, CAS 107-87-9) is a five-carbon aliphatic ketone with the molecular formula CH3COCH2CH2CH3. It is produced industrially by the oxidation of 2-pentanol or by the catalytic dehydrogenation of secondary amyl alcohol. The commercial product is a clear, colorless liquid with a characteristic ketone odor similar to acetone but milder.

2-Pentanone is a versatile solvent with moderate evaporation rate, good solvency for resins and polymers, and partial water miscibility (approximately 5-6 g/100 mL at 20°C). Its evaporation rate falls between acetone (very fast) and MIBK (slower), making it useful in formulations where controlled drying is required. The ketone carbonyl group also enables 2-pentanone to participate in condensation, reduction, and Grignard reactions as a chemical intermediate.

Specifications

Each batch is tested by gas chromatography for purity, Karl Fischer for water, and density measurement. A COA is provided with every shipment.

Applications

Solvent for Coatings & Inks

2-Pentanone is used as a solvent in nitrocellulose lacquers, acrylic coatings, epoxy resins, and printing inks. Its moderate evaporation rate provides good flow and leveling without causing blushing or pinholing. It is often blended with other ketones and alcohols to optimize drying time and film properties. Typical usage in coating formulations is 5-30% by weight.

Adhesives & Sealants

Solvent for pressure-sensitive adhesives, contact adhesives, and rubber-based sealants. 2-Pentanone dissolves natural rubber, SBR, and acrylic polymers efficiently. Its fast evaporation allows rapid bond development while maintaining adequate open time for assembly.

Extraction & Purification

Extraction solvent for pharmaceuticals, antibiotics, and natural products. 2-Pentanone’s partial water miscibility and high solvency for organic compounds make it effective for liquid-liquid extraction. It is also used as a recrystallization solvent and as a cleaning agent for precision parts and electronic components.

Chemical Synthesis

Intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. 2-Pentanone undergoes aldol condensation, reduction to 2-pentanol, and reaction with amines to form imines and enamines. It is also used as a reagent in the synthesis of fragrances and flavor compounds.

Safety, Handling & Storage

2-Pentanone is a highly flammable liquid (flash point 7°C) and can form explosive vapor-air mixtures. Store in a cool, well-ventilated, fire-resistant area away from heat, sparks, open flames, and oxidizing agents. Keep containers tightly sealed and electrically grounded. Storage temperature should not exceed 30°C. Use only non-sparking tools and explosion-proof equipment in handling areas.

Wear chemical goggles, face shield, nitrile gloves, and protective clothing. Use in a well-ventilated area or with local exhaust ventilation. Avoid inhalation of vapors, which may cause dizziness, headache, and central nervous system depression. In case of eye contact, flush with water for 15 minutes. In case of fire, use alcohol-resistant foam, dry chemical, or CO2 extinguishers. 2-Pentanone is classified as UN 1249, Class 3 (Flammable Liquid) for transport.

FAQ

What is the difference between 2-pentanone and 3-pentanone?

2-Pentanone (methyl propyl ketone) has the carbonyl group at the 2-position, while 3-pentanone (diethyl ketone) has it at the 3-position. They have similar boiling points (102°C vs 101°C) and solvent properties, but 2-pentanone is more reactive due to the methyl group adjacent to the carbonyl, making it more suitable for condensation reactions. 2-Pentanone is also more widely available industrially.

Can 2-pentanone be used as a replacement for MEK or MIBK?

2-Pentanone can serve as a partial replacement for MEK (methyl ethyl ketone) or MIBK (methyl isobutyl ketone) in many solvent applications. Its evaporation rate is between MEK (faster) and MIBK (slower). However, formulation adjustments may be needed due to differences in solvency, water miscibility, and regulatory status. Always conduct compatibility testing before full substitution.

What is the minimum order quantity?

Standard packaging is 160 kg steel drums and 1000 L IBC totes. Full container loads (20-24 tons) are typical for bulk orders. ISO tank containers are available for large-volume customers. Smaller quantities are available for sample and qualification testing.