Triclocarban Powder CAS 101-20-2

Triclocarban Powder is a broad-spectrum antimicrobial agent supplied as a white to off-white crystalline powder. It combines high thermal stability with low water solubility to deliver long-lasting residual activity against Gram-positive bacteria including Staphylococcus aureus and MRSA. It serves as a key ingredient in industrial disinfectants, antimicrobial polymer compounds and medical textile finishes. UETChem supplies high-purity triclocarban with strict quality controls for consistent antimicrobial performance. Each shipment includes COA, TDS, SDS.

  • CAS No: 101-20-2
  • Synonyms: 3,4,4′-Trichlorocarbanilide; TCC; Trichlorocarbanilide
  • EC Number: 202-924-5
  • Molecular Formula: C₁₃H₉Cl₃N₂O
  • Molecular Weight: 315.58 g/mol
  • Appearance: White to off-white crystalline powder
  • Purity (HPLC): ≥ 99.0%
  • Heavy Metals: ≤ 10 ppm
  • Packaging: 1 kg foil bag; 5 kg / 25 kg fiber drum. Custom packaging available.
  • Main Applications: Industrial & institutional disinfectants, antimicrobial polymer additives, medical textile finishing, professional hygiene formulations
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Introduction to Triclocarban

Triclocarban (TCC) is a chlorinated diphenyl urea derivative with potent bacteriostatic and bactericidal activity, especially against Gram-positive organisms. Its extremely low aqueous solubility creates strong binding affinity to surfaces, skin and polymer matrices, delivering prolonged residual antimicrobial effect. While consumer over-the-counter antiseptic use is restricted in some regions, it remains a valued active ingredient for industrial, institutional and professional applications requiring long-term surface protection and thermal processing stability.

The material shows excellent stability under heat and UV exposure, making it suitable for incorporation into melt-processed plastics and synthetic fibers. Dry powder storage stability is good, but it must be protected from excessive moisture and strong oxidizing agents to prevent urea bond cleavage. Store in sealed, moisture-proof containers below 25 °C.

Triclocarban Chemical & Physical Properties

Property Value
Molecular Formula C₁₃H₉Cl₃N₂O
Molecular Weight 315.58 g/mol
Melting Point 254 – 256 °C
Crystal Density Approx. 1.49 g/cm³
Water Solubility Practically insoluble (~0.5 mg/L at 25 °C)
Solvent Solubility Soluble in ethanol, acetone, DMSO, DMF
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 10 ppm

Applications of Triclocarban

Industrial & institutional surface disinfection
Formulated into heavy-duty disinfectant concentrates and wipes for healthcare facilities, veterinary clinics and food processing plants. It provides residual bacteriostatic protection on hard surfaces between regular cleaning cycles.

Antimicrobial polymer & plastic additives
Incorporated into PVC, polyurethane and silicone to manufacture antimicrobial medical tubing, hospital bed rails and appliance seals. Its high thermal stability preserves full efficacy through standard high-temperature melt processing.

Medical textile & nonwoven finishing
Applied to surgical gowns, drapes and industrial filter media via exhaust or pad-dry-cure methods. It binds strongly to synthetic fibers, preventing bacterial colonization and odor buildup in high-humidity environments.

Professional topical & occupational hygiene
Used as an active biostatic agent in industrial hand cleaners, veterinary shampoos and occupational barrier creams. It deposits onto the skin surface to deliver extended protection against workplace pathogens.

Storage & Safety Precautions for Triclocarban

  • Keep tightly sealed in original packaging in a cool, dry, well-ventilated area below 25 °C. Protect from direct sunlight and strong oxidizing agents. Shelf life exceeds 36 months under proper conditions. Avoid moisture ingress which can cause powder caking.
  • Harmful if swallowed and very toxic to aquatic life with long-lasting effects. Avoid generating dust during weighing and blending. Wear N95 respirators, nitrile gloves and safety goggles during handling. Wash hands thoroughly after use.
  • Generally classified as Non-DG for standard freight, but may require environmental hazard labeling in some jurisdictions due to aquatic toxicity. Secure pallets and protect from moisture during transit.
  • Verify identity via HPLC retention time and melting point upon receipt. Confirm purity ≥ 99.0% and moisture ≤ 0.5%. Greyish or yellowish discoloration may indicate thermal or oxidative degradation.

Triclocarban FAQ

Q: How does Triclocarban differ from Triclosan in polymer applications?

A: Triclocarban has a much higher melting point (~255 °C vs ~57 °C for triclosan), so it withstands high-temperature plastic extrusion without degrading. It is more active against Gram-positive bacteria, while triclosan covers more Gram-negative strains.

Q: Can Triclocarban be added directly to water-based formulations?

A: No. It is nearly insoluble in water and will precipitate if added directly. It must first be dissolved in co-solvents or surfactant blends to form a stable concentrate before dilution into aqueous products.

Q: Is Triclocarban approved for consumer cosmetic products?

A: Regulatory status varies by region. It is restricted in over-the-counter consumer antiseptic washes in some markets, but remains approved for industrial, institutional and medical device applications globally. Always verify local biocide regulations before use.

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