Hydroxyecdysone CAS 5289-74-7

Hydroxyecdysone is a plant-derived steroidal ecdysteroid bioactive for cosmetic and personal care formulations. It supports skin renewal, collagen synthesis and hair follicle metabolism, delivering anti-aging, barrier repair and hair strengthening benefits. UETChem supplies high-purity hydroxyecdysone with strict impurity controls for consistent efficacy in skincare and haircare products. Each shipment includes COA, TDS, SDS.

  • CAS No: 5289-74-7
  • Synonyms: β-Ecdysone; 20-Hydroxyecdysone; Ecdysterone; 20-Hydroxy-β-ecdysone
  • EINECS: 226-130-3
  • Molecular Formula: C₂₇H₄₄O₇
  • Molecular Weight: 480.63 g/mol
  • Appearance: White to off-white crystalline powder
  • Purity: 98.0% min (HPLC)
  • Loss on Drying: 0.5% max
  • Packaging: 1 kg foil bag, 25 kg drum. Custom packaging available upon request.
  • Main Applications: Anti-aging skincare, hair care actives, skin repair formulations, cosmetic bioactive additives
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Introduction to Hydroxyecdysone

Hydroxyecdysone, also known as ecdysterone, is a naturally occurring steroidal ecdysteroid typically extracted from botanical sources such as Cyanotis arachnoidea. It promotes keratinocyte proliferation, stimulates collagen production and supports epidermal barrier function. It appears as a white to off-white crystalline powder at room temperature, soluble in alcohols and slightly soluble in water.

It is widely used in premium cosmetic formulations to improve skin texture and reduce fine lines, and supports hair follicle health for stronger, more resilient hair. The material is sensitive to UV light and elevated temperatures, which may degrade bioactivity over extended exposure.

Hydroxyecdysone Chemical & Physical Properties

Property Value
Molecular Formula C₂₇H₄₄O₇
Molecular Weight 480.63 g/mol
Appearance White to off-white crystalline powder
Melting Point 242 – 244 °C
Purity (HPLC) 98.0% min
Solubility Soluble in ethanol/methanol; slightly soluble in water
Loss on Drying 0.5% max

Applications of Hydroxyecdysone

Anti-aging skincare: Incorporated into serums, creams and essences to promote skin cell renewal and collagen synthesis. It helps improve texture, reduce fine lines and support dermal structural integrity.

Hair care formulations: Added to shampoos, conditioners and hair tonics to support scalp and follicle metabolism. It contributes to stronger strands and reduced breakage for fuller, healthier-looking hair.

Skin repair products: Used in barrier repair and soothing formulations to support skin recovery. It helps reinforce the epidermal barrier and improve resilience against environmental stressors.

Premium personal care: Featured in high-end cosmetics as a functional bioactive, combining revitalization benefits with good compatibility in both aqueous and oil-based systems.

Storage & Safety Precautions for Hydroxyecdysone

  • Store in tightly sealed, light-resistant containers in a cool, dry place below 25 °C. Protect from direct sunlight, high humidity and heat to prevent degradation and activity loss.
  • Wear safety goggles, dust masks and nitrile gloves during bulk powder handling. Avoid dust inhalation and direct contact with eyes and skin.
  • Keep away from strong oxidizers and extreme pH conditions. Store separately from food and feed materials to avoid cross-contamination.

Hydroxyecdysone FAQ

Q: What skincare benefits does Hydroxyecdysone provide?

A: It boosts cell renewal and collagen production, improving fine lines, texture and barrier strength for anti-aging effects.

Q: Is Hydroxyecdysone a plant-derived ingredient?

A: Yes, it is typically extracted from botanical sources and standardized to high purity grades.

Q: How should Hydroxyecdysone be stored to retain activity?

A: Store sealed in cool, dark, dry conditions. Protect from light and heat to prevent bioactivity degradation.

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